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Flexeril prices as low as $79 including a free USA doctor consultation. Overnight shipping available. FedEx Express shipping is available along with other shipping options.
Contains 10mg cyclobenzaprine. Ortho-McNeil currently has exclusive rights to the 5mg version |
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Acquired by Alza Corporation from Merck in 2001 (press release - had to dig for this!) |
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| Alza Corp. is developing a controlled-release Flexeril version with its OROS® technology. OROS® osmotic technology provides more controlled therapeutic drug levels in the blood throughout the dosing interval. | ||
Designed for relaxing muscles to relieve pain associated with sprains, strains, and other muscle injuries |
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Approved by FDA in November, 1977 |
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| Cyclobenzaprine is closely related to the tricyclic antidepressants amitriptyline and imipramine | ||
| Not scheduled by the DEA as a controlled substance |
The following informative paragraphs are from RxList's Cyclobenzaprine Clinical Pharmacology page. When daily observations were made, clinical improvement was observed as early as the first day of therapy. Controlled clinical studies show that cyclobenzaprine HCl significantly improves the signs and symptoms of skeletal muscle spasm as compared with placebo. The clinical responses include improvement in muscle spasm as determined by palpation, reduction in local pain and tenderness, increased range of motion, and less restriction in activities of daily living. It reports in three out of eight studies Flexeril was better than Valium for relieving spasm and pain local to muscles.
Eight double-blind controlled clinical studies were performed in 642 patients comparing cyclobenzaprine HCl, diazepam, and placebo. Muscle spasm, local pain and tenderness, limitation of motion, and restriction in activities of daily living were evaluated. In three of these studies there was a significantly greater improvement with cyclobenzaprine HCl than with diazepam (Valium), while in the other studies the improvement following both treatments was comparable.
Analysis of the data from controlled studies shows that cyclobenzaprine HCl produces clinical improvement whether or not sedation occurs.
Although the frequency and severity of adverse reactions observed in patients treated with cyclobenzaprine HCl were comparable to those observed in patients treated with diazepam, dry mouth was observed more frequently in patients treated with cyclobenzaprine HCl and dizziness more frequently in those treated with diazepam. The incidence of drowsiness, the most frequent adverse reaction, was similar with both drugs.
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